hrp0095p1-56 | Diabetes and Insulin | ESPE2022

Curative effect contributors of exercise in type one diabetes: Irisin and Sestrin

Ceyhun Emre , Devran Sergen , Can Demirbaş Kaan , Çıkıkçı Alper , Güven Günver Mehmet , Güneş Kaya Didem , Bayramoğlu Elvan , Bayraktar Bülent , Quinn Maryanne , Olcay Evliyaoglu Saadet

Type 1 Diabetes (T1DM) is a chronic metabolic disease characterized by hyperglycemia due to absolute insulin deficiency as a result of autoimmune damage of pancreatic β cells. In its treatment, insulin, medical nutrition therapy and exercise is recommended. Although it is known that exercise contributes to disease control, the mechanism of these effects has not been fully clarified. It is thought that myokines such as irisin and sestrin, can be effective by secreting with...